What is Neurofibromatosis
Posted by
writer on Thursday 16 Apr 2009
Neurofibromatosis is genetic disorder. In this condition the tumors are formed on the nerves in the entire body. This condition can also lead to the upshot the development of skin and bones, this can lead to disfigurement in the long run. The levels are different in each of the stages and the severity and the pain also varies. In most of the cases it can lead to disability in learning and even blindness and deafness.
Neurofibromatosis’s used for the autosomal human disorder which relates to the disorder in growth of cells in the neural crest source. With the formation of neurofibromas the tumors can begin and can spread to any nerve of the body. They can include even in any of the bone structure. One can observe varying degrees of mental retardation. In most of the cases the tumors are benign but in the later stages can transform into malignancies.
In most of the condition this is inherited, but it also has been observed that in 30-50% cases it happens on account of mutation in the individual gene structure. With the change the mutating gene can later pass to the next generations. Due to this gene numerous other kind of cancer can arise, with multiple complications. In the infancy the disease may appear like café-au-lait spots. In the later period somewhere in puberty one can see the characteristic manifestations. They can be seen like pigmented nevi or moles. Even the adult can be seen with pendulous mass of the skin in most of the cases.
Signs of Neurofibromatosis:-
Very high rate of speech impairment, along with learning disabilities. The kid may also suffer from attention deficit disorder. Seizure disorder and accumulation of fluid in the brain. Brain tumors, leukemia, tumors of muscles and adrenal glands and kidneys are also seen in such patients.
Skin spots like moles, freckling can be seen. Loss of hearing, weakness in facial muscles, dizziness, headache, poor balance and cloudy areas in the eyes can be seen.
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